5C7X: Crystal structure of MOR04357, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF

PDB ID: 5C7XDownload
MMDB ID: 133345
PDB Deposition Date: 2015/6/25
Updated in MMDB: 2015/11
Experimental Method:
x-ray diffraction
Resolution: 2.95  Å
Source Organism:
Similar Structures:
Biological Unit for 5C7X: trimeric; determined by author and by software (PISA)
Molecular Components in 5C7X
Label Count Molecule
Proteins (3 molecules)
1
Granulocyte-macrophage Colony-stimulating Factor
(Gene symbol: CSF2)
Molecule annotation
1
Immunglobulin G1 FAB Fragment, Heavy Chain
Molecule annotation
1
Immunglobulin G1 FAB Fragment, Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
2
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
1
1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303