5DEW: Crystal structure of PAK1 in complex with an inhibitor compound 5

PDB ID: 5DEWDownload
MMDB ID: 143210
PDB Deposition Date: 2015/8/26
Updated in MMDB: 2016/09
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5DEW: monomeric; determined by author and by software (PISA)
Molecular Components in 5DEW
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase PAK 1
(Gene symbol: PAK1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
8-[(trans-4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8H)-one8-[(trans-4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303