5FBV: PI4KB in complex with Rab11 and the MI364 Inhibitor

PDB ID: 5FBVDownload
MMDB ID: 145945
PDB Deposition Date: 2015/12/14
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 3.285  Å
Source Organism:
Similar Structures:
Biological Unit for 5FBV: dimeric; determined by author and by software (PISA)
Molecular Components in 5FBV
Label Count Molecule
Proteins (2 molecules)
1
Phosphatidylinositol 4-kinase Beta,phosphatidylinositol 4-kinase Beta
(Gene symbol: PI4KB)
Molecule annotation
1
Ras-related Protein Rab-11a
(Gene symbol: RAB11A)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
~{N}-[2-[[6-chloranyl-3-[3-(2-hydroxyethylsulfamoyl)-4-methoxy-phenyl]-2-methyl-imidazo[1,2-b]pyridazin-8-yl]amino]ethy l]ethanamide~{N}-[2-[[6-chloranyl-3-[3-(2-hydroxyethylsulfamoyl)-4-methoxy-phenyl]-2-methyl-imidazo[1,2-b]pyridazin-8-yl]amino]ethy l]ethanamide
2
1
5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303