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5FN3:
Cryo-EM structure of gamma secretase in class 1 of the apo- state ensemble
PDB ID:
5FN3
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MMDB ID:
134934
PDB Deposition Date:
2015/11/10
Updated in MMDB:
2016/12
Experimental Method:
electron microscopy
Resolution:
4.1 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Molecular Components in 5FN3
Label
Count
Molecule
Proteins (5 molecules)
A
1
Nicastrin
(Gene symbol:
NCSTN
)
B
1
Presenilin-1
(Gene symbol:
PSEN1
)
C
1
Gamma-secretase Subunit Aph-1a
(Gene symbol:
APH1A
)
D
1
Gamma-secretase Subunit Pen-2
(Gene symbol:
PSENEN
)
G
1
Poly ALA Chain
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303