5G53: Structure of the adenosine A2A receptor bound to an engineered G protein

PDB ID: 5G53Download
MMDB ID: 241193
PDB Deposition Date: 2016/5/19
Updated in MMDB: 2024/01
Experimental Method:
x-ray diffraction
Resolution: 3.4  Å
Source Organism:
Similar Structures:
Biological Unit for 5G53: dimeric; determined by author and by software (PISA)
Molecular Components in 5G53
Label Count Molecule
Proteins (2 molecules)
1
Adenosine Receptor A2A
(Gene symbol: ADORA2A)
Molecule annotation
1
Engineered Domain of Human G Alpha S Long Isoform
(Gene symbol: GNAS)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
N-ETHYL-5'-CARBOXAMIDO ADENOSINEN-ETHYL-5'-CARBOXAMIDO ADENOSINE
2
2
octyl 1-thio-beta-D-glucopyranosideoctyl 1-thio-beta-D-glucopyranoside
3
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303