5H8H: Structure of the human GluN1/GluN2A LBD in complex with GNE3419

PDB ID: 5H8HDownload
MMDB ID: 136793
PDB Deposition Date: 2015/12/23
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.23  Å
Source Organism:
Similar Structures:
Biological Unit for 5H8H: dimeric; determined by author and by software (PISA)
Molecular Components in 5H8H
Label Count Molecule
Proteins (2 molecules)
1
Glutamate Receptor Ionotropic, Nmda 2a,glutamate Receptor Ionotropic, Nmda 2A
(Gene symbol: GRIN2A)
Molecule annotation
1
Glutamate Receptor Ionotropic, Nmda 1,glutamate Receptor Ionotropic, Nmda 1
(Gene symbol: GRIN1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
ACETATE IONACETATE ION
2
1
GLUTAMIC ACIDGLUTAMIC ACID
3
1
CALCIUM IONCALCIUM ION
4
1
GLYCINEGLYCINE
5
1
7-[[ethyl(phenyl)amino]methyl]-2-methyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one7-[[ethyl(phenyl)amino]methyl]-2-methyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303