5H8Q: Structure of the human GluN1/GluN2A LBD in complex with GNE8324

PDB ID: 5H8QDownload
MMDB ID: 136795
PDB Deposition Date: 2015/12/23
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5H8Q: dimeric; determined by author and by software (PISA)
Molecular Components in 5H8Q
Label Count Molecule
Proteins (2 molecules)
1
Glutamate Receptor Ionotropic, Nmda 2a,glutamate Receptor Ionotropic, Nmda 2A
(Gene symbol: GRIN2A)
Molecule annotation
1
Glutamate Receptor Ionotropic, Nmda 1,glutamate Receptor Ionotropic, Nmda 1
(Gene symbol: GRIN1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ACETATE IONACETATE ION
2
1
GLUTAMIC ACIDGLUTAMIC ACID
3
1
GLYCINEGLYCINE
4
1
6-[[ethyl-(4-fluorophenyl)amino]methyl]-2,3-dihydro-1~{H}-cyclopenta[3,4][1,3]thiazolo[1,4-~{a}]pyrimidin-8-one6-[[ethyl-(4-fluorophenyl)amino]methyl]-2,3-dihydro-1~{H}-cyclopenta[3,4][1,3]thiazolo[1,4-~{a}]pyrimidin-8-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303