5J71: Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS35

PDB ID: 5J71Download
MMDB ID: 146782
PDB Deposition Date: 2016/4/5
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 5J71: dimeric; determined by author and by software (PISA)
Molecular Components in 5J71
Label Count Molecule
Proteins (2 molecules)
2
[pyruvate Dehydrogenase (Acetyl-transferring)] Kinase Isozyme 2, Mitochondrial
(Gene symbol: PDK2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
L(+)-TARTARIC ACIDL(+)-TARTARIC ACID
2
2
4-({5-[(piperidin-4-yl)amino]-1,3-dihydro-2H-isoindol-2-yl}sulfonyl)benzene-1,3-diol4-({5-[(piperidin-4-yl)amino]-1,3-dihydro-2H-isoindol-2-yl}sulfonyl)benzene-1,3-diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303