5KWY: Structure of human NPC1 middle lumenal domain bound to NPC2

PDB ID: 5KWYDownload
MMDB ID: 142333
PDB Deposition Date: 2016/7/19
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.405  Å
Source Organism:
Similar Structures:
Biological Unit for 5KWY: tetrameric; determined by author and by software (PISA)
Molecular Components in 5KWY
Label Count Molecule
Proteins (4 molecules)
2
Niemann-pick C1 Protein
(Gene symbol: NPC1)
Molecule annotation
2
Epididymal Secretory Protein E1
(Gene symbol: NPC2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
CHOLEST-5-EN-3-YL HYDROGEN SULFATECHOLEST-5-EN-3-YL HYDROGEN SULFATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303