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Biotechnology Information

5L5O: Yeast 20S proteasome with human beta5i (1-138) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 16

PDB ID:

MMDB ID:

144787

PDB Deposition Date:

2016/5/28

Updated in MMDB:

2016/12

Experimental Method:

x-ray diffraction

Resolution:

2.6 Å

Source Organism:

Saccharomyces cerevisiae S288C▼

Taxonomy	Molecule
Saccharomyces cerevisiae S288C	A, B, C, D, E, F, G, H, I, J, M, N, O, P, Q, R, S, T, U, V, W, X, a, b
synthetic construct	K, L, Y, Z

Similar Structures:

Biological Unit for 5L5O: 28-meric; determined by author

Molecular Components in 5L5O
Label	Count	Molecule
Proteins (28 molecules)
A O	2	Proteasome Subunit Alpha Type-2
B P	2	Proteasome Subunit Alpha Type-3
C Q	2	Proteasome Subunit Alpha Type-4
D R	2	Proteasome Subunit Alpha Type-5
E S	2	Proteasome Subunit Alpha Type-6
F T	2	Probable Proteasome Subunit Alpha Type-7
G U	2	Proteasome Subunit Alpha Type-1
H V	2	Proteasome Subunit Beta Type-2
I W	2	Proteasome Subunit Beta Type-3
J X	2	Proteasome Subunit Beta Type-4
K Y	2	Proteasome Subunit Beta Type-8,proteasome Subunit Beta Type-5
L Z	2	Proteasome Subunit Beta Type-6,proteasome Subunit Beta Type-1,proteasome Subunit Beta Type-6,proteasome Subunit Beta Type-1,proteasome Subunit Beta Type-6
M a	2	Proteasome Subunit Beta Type-7
N b	2	Proteasome Subunit Beta Type-1
Chemicals and Non-standard biopolymers (16 molecules)
1	8	MAGNESIUM ION
2	2	CHLORIDE ION
3	4	(2~{S})-3-(1~{H}-indol-3-yl)-~{N}-[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{R})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide
4	2	2-(N-MORPHOLINO)-ETHANESULFONIC ACID

* Click molecule labels to explore molecular sequence information.

Citing MMDB