5M4Z: Crystal structure of the complex of T.spiralis thymidylate synthase with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate, crystallized in the presence of N(5,10)-methylenetetrahydrofolate

PDB ID: 5M4ZDownload
MMDB ID: 157365
PDB Deposition Date: 2016/10/19
Updated in MMDB: 2018/06
Experimental Method:
x-ray diffraction
Resolution: 1.179  Å
Source Organism:
Similar Structures:
Biological Unit for 5M4Z: dimeric; determined by author and by software (PISA)
Molecular Components in 5M4Z
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
(Gene symbol: Tsp_03568)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
[(2~{R},3~{S},5~{R})-5-[(4~{E})-4-hydroxyimino-2-oxidanylidene-1,3-diazinan-1-yl]-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate[(2~{R},3~{S},5~{R})-5-[(4~{E})-4-hydroxyimino-2-oxidanylidene-1,3-diazinan-1-yl]-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate
2
5
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303