5M6U: HUMAN PI3KDELTA IN COMPLEX WITH LASW1579

PDB ID: 5M6UDownload
MMDB ID: 147006
PDB Deposition Date: 2016/10/26
Updated in MMDB: 2019/03
Experimental Method:
x-ray diffraction
Resolution: 2.85  Å
Source Organism:
Similar Structures:
Biological Unit for 5M6U: dimeric; determined by author and by software (PISA)
Molecular Components in 5M6U
Label Count Molecule
Proteins (2 molecules)
1
Phosphatidylinositol 4,5-bisphosphate 3-kinase Catalytic Subunit Delta Isoform
(Gene symbol: PIK3CD)
Molecule annotation
1
Phosphatidylinositol 3-kinase Regulatory Subunit Alpha
(Gene symbol: PIK3R1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-azanyl-6-[[(1~{S})-1-(4-oxidanylidene-3-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile4-azanyl-6-[[(1~{S})-1-(4-oxidanylidene-3-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303