5MU8: HUMAN TNF-ALPHA IN COMPLEX WITH JNJ525

PDB ID: 5MU8Download
MMDB ID: 149097
PDB Deposition Date: 2017/1/12
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 5MU8: tetrameric; determined by software (PISA)
Molecular Components in 5MU8
Label Count Molecule
Proteins (4 molecules)
4
Tumor Necrosis Factor
(Gene symbol: TNF)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
7
~{N}4-(phenylmethyl)-~{N}4-[2-[3-(2-piperazin-1-ylpyrimidin-5-yl)phenyl]phenyl]pyrimidine-2,4-diamine (Link to PubChem not yet available)~{N}4-(phenylmethyl)-~{N}4-[2-[3-(2-piperazin-1-ylpyrimidin-5-yl)phenyl]phenyl]pyrimidine-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303