5N23: Protein kinase A mutants as surrogate model for Aurora B with AT9283 inhibitor

PDB ID: 5N23Download
MMDB ID: 160087
PDB Deposition Date: 2017/2/7
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 2.088  Å
Source Organism:
Similar Structures:
Biological Unit for 5N23: dimeric; determined by author and by software (PISA)
Molecular Components in 5N23
Label Count Molecule
Proteins (2 molecules)
1
Camp-dependent Protein Kinase Catalytic Subunit Alpha
(Gene symbol: PRKACA)
Molecule annotation
1
Camp-dependent Protein Kinase Inhibitor Alpha
(Gene symbol: PKIA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303