5NX1: Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy

PDB ID: 5NX1Download
MMDB ID: 162660
PDB Deposition Date: 2017/5/9
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.853  Å
Source Organism:
Similar Structures:
Molecular Components in 5NX1
Label Count Molecule
Proteins (4 molecules)
1
Kallikrein-6
(Gene symbol: KLK6)
Molecule annotation
1
Amyloid-beta A4 Protein
(Gene symbol: APP)
Molecule annotation
1
Amyloid-beta A4 Protein
(Gene symbol: APP)
Molecule annotation
1
Amyloid-beta A4 Protein
(Gene symbol: APP)
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303