5OLB: crystal structure of autotaxin in complex with PF-8380

PDB ID: 5OLBDownload
MMDB ID: 157866
PDB Deposition Date: 2017/7/27
Updated in MMDB: 2024/01
Experimental Method:
x-ray diffraction
Resolution: 1.82  Å
Source Organism:
Similar Structures:
Biological Unit for 5OLB: monomeric; determined by author and by software (PISA)
Molecular Components in 5OLB
Label Count Molecule
Protein (1 molecule)
1
Ectonucleotide Pyrophosphatase/phosphodiesterase Family Member 2
(Gene symbol: Enpp2)
Molecule annotation
Chemicals and Non-standard biopolymers (25 molecules)
1
6
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
beta-D-mannopyranosebeta-D-mannopyranose
3
4
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
alpha-L-fucopyranosealpha-L-fucopyranose
5
2
ZINC IONZINC ION
6
2
CALCIUM IONCALCIUM ION
7
2
SODIUM IONSODIUM ION
8
1
POTASSIUM IONPOTASSIUM ION
9
1
CHLORIDE IONCHLORIDE ION
10
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
11
1
SULFATE IONSULFATE ION
12
1
(3,5-dichlorophenyl)methyl 4-[3-oxo-3-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)propyl]piperazine-1-carboxylate(3,5-dichlorophenyl)methyl 4-[3-oxo-3-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)propyl]piperazine-1-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303