5PAX: Crystal Structure of Factor VIIa in complex with 1-(2,6-difluorophenyl)-3-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]urea

PDB ID: 5PAXDownload
MMDB ID: 151984
PDB Deposition Date: 2016/11/10
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.36  Å
Source Organism:
Similar Structures:
Biological Unit for 5PAX: dimeric; determined by author
Molecular Components in 5PAX
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor VII Light Chain
(Gene symbol: F7)
Molecule annotation
1
Coagulation Factor VII Heavy Chain
(Gene symbol: F7)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
GLYCEROLGLYCEROL
2
1
CALCIUM IONCALCIUM ION
3
1
CHLORIDE IONCHLORIDE ION
4
2
SULFATE IONSULFATE ION
5
1
1-(2,6-difluorophenyl)-3-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]urea1-(2,6-difluorophenyl)-3-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303