5PB0: Crystal Structure of Factor VIIa in complex with 2-(4-ethoxy-3-methoxyphenyl)-2-(isoquinolin-6-ylamino)acetic acid

PDB ID: 5PB0Download
MMDB ID: 151986
PDB Deposition Date: 2016/11/10
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.98  Å
Source Organism:
Similar Structures:
Biological Unit for 5PB0: dimeric; determined by author
Molecular Components in 5PB0
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor VII Light Chain
(Gene symbol: F7)
Molecule annotation
1
Coagulation Factor VII Heavy Chain
(Gene symbol: F7)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
3
CHLORIDE IONCHLORIDE ION
2
5
SULFATE IONSULFATE ION
3
1
GLYCEROLGLYCEROL
4
1
(2~{R})-2-(4-ethoxy-3-methoxy-phenyl)-2-(isoquinolin-6-ylamino)ethanoic acid(2~{R})-2-(4-ethoxy-3-methoxy-phenyl)-2-(isoquinolin-6-ylamino)ethanoic acid
5
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303