5QQO: FACTOR XIA IN COMPLEX WITH THE INHIBITOR methyl [(5E,8S)-8-[(6R)-6-(3-chlorophenyl)-2-oxo-1,3-oxazinan-3-yl]-2-oxo-1,3,4,7,8,10-hexahydro-2H-12,9-(azeno)-1,10-benzodiazacyclotetradecin-15-yl]carbamate

PDB ID: 5QQODownload
MMDB ID: 179447
PDB Deposition Date: 2019/5/20
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 5QQO: dimeric; determined by author and by software (PISA)
Molecular Components in 5QQO
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor XI
(Gene symbol: F11)
Molecule annotation
1
Met-asp-asp-asp-asp-lys-met-asp-asn-glu-cys-thr-thr-lys-ile-lys-pro-arg
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
1
methyl [(5E,8S)-8-[(6R)-6-(3-chlorophenyl)-2-oxo-1,3-oxazinan-3-yl]-2-oxo-1,3,4,7,8,10-hexahydro-2H-12,9-(azeno)-1,10-benzodiazacyclotetradecin-15-yl]carbamatemethyl [(5E,8S)-8-[(6R)-6-(3-chlorophenyl)-2-oxo-1,3-oxazinan-3-yl]-2-oxo-1,3,4,7,8,10-hexahydro-2H-12,9-(azeno)-1,10-benzodiazacyclotetradecin-15-yl]carbamate
2
1
SULFATE IONSULFATE ION
3
12
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303