5T8F: p110delta/p85alpha with taselisib (GDC-0032)

PDB ID: 5T8FDownload
MMDB ID: 146334
PDB Deposition Date: 2016/9/7
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.91  Å
Source Organism:
Bos taurus▼
Similar Structures:
Biological Unit for 5T8F: dimeric; determined by author and by software (PISA)
Molecular Components in 5T8F
Label Count Molecule
Proteins (2 molecules)
1
Phosphatidylinositol 4,5-bisphosphate 3-kinase Catalytic Subunit Delta Isoform
Molecule annotation
1
Phosphatidylinositol 3-kinase Regulatory Subunit Alpha
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-methyl-2-(4-{2-[3-methyl-1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-1H-pyrazol-1-yl)propanamide2-methyl-2-(4-{2-[3-methyl-1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-1H-pyrazol-1-yl)propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303