5TUY: Structure of human G9a SET-domain (EHMT2) in complex with inhibitor MS0124

PDB ID: 5TUYDownload
MMDB ID: 147583
PDB Deposition Date: 2016/11/7
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 5TUY: dimeric; determined by author and by software (PISA)
Molecular Components in 5TUY
Label Count Molecule
Proteins (2 molecules)
2
Histone-lysine N-methyltransferase Ehmt2
(Gene symbol: EHMT2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
8
ZINC IONZINC ION
2
2
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
3
2
6,7-dimethoxy-N-(1-methylpiperidin-4-yl)-2-(morpholin-4-yl)quinazolin-4-amine6,7-dimethoxy-N-(1-methylpiperidin-4-yl)-2-(morpholin-4-yl)quinazolin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303