5USQ: ALK-5 kinase inhibitor complex

PDB ID: 5USQDownload
MMDB ID: 149788
PDB Deposition Date: 2017/2/13
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.55  Å
Source Organism:
Similar Structures:
Biological Unit for 5USQ: monomeric; determined by author and by software (PISA)
Molecular Components in 5USQ
Label Count Molecule
Protein (1 molecule)
1
Tgf-beta Receptor Type-1
(Gene symbol: TGFBR1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[2-(5-chloro-2-fluorophenyl)pyridin-4-yl]-2-[(piperidin-4-yl)methyl]-2H-pyrazolo[4,3-b]pyridin-7-amineN-[2-(5-chloro-2-fluorophenyl)pyridin-4-yl]-2-[(piperidin-4-yl)methyl]-2H-pyrazolo[4,3-b]pyridin-7-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303