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5X24:
Crystal structure of CYP2C9 genetic variant I359L (*3) in complex with multiple losartan molecules
PDB ID:
5X24
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MMDB ID:
155435
PDB Deposition Date:
2017/1/30
Updated in MMDB:
2023/11
Experimental Method:
x-ray diffraction
Resolution:
2.48 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 5X24: monomeric; determined by author and by software (PISA)
Molecular Components in 5X24
Label
Count
Molecule
Protein (1 molecule)
A
1
Cytochrome P450 2C9
(Gene symbol:
CYP2C9
)
Chemicals and Non-standard biopolymers (5 molecules)
1
1
PROTOPORPHYRIN IX CONTAINING FE
2
2
[2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
3
1
PHOSPHATE ION
4
1
POTASSIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303