National Center for
Biotechnology Information

5ZWO: Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom

PDB ID:	5ZWO Download
MMDB ID:	166092
PDB Deposition Date:	2018/5/16
Updated in MMDB:	2022/11
Experimental Method:	electron microscopy
Resolution:	3.9 Å
Source Organism:	Saccharomyces cerevisiae S288C
Similar Structures:

Biological Unit for 5ZWO: 60-meric; determined by author

Molecular Components in 5ZWO
Label	Count	Molecule
Proteins (55 molecules)
A	1	Pre-mrna-splicing Factor 8 (Gene symbol: PRP8)
K	1	U4/u6 Small Nuclear Ribonucleoprotein Prp4 (Gene symbol: PRP4)
L	1	Pre-mrna-processing Factor 31 (Gene symbol: PRP31)
N	1	Pre-mrna-splicing Factor 6 (Gene symbol: PRP6)
J	1	U4/u6 Small Nuclear Ribonucleoprotein Prp3 (Gene symbol: PRP3)
E	1	Spliceosomal Protein Dib1 (Gene symbol: DIB1)
M	1	13 KDA Ribonucleoprotein-associated Protein (Gene symbol: SNU13)
C	1	Pre-mrna-splicing Factor Snu114 (Gene symbol: SNU114)
z	1	U6 Snrna-associated Sm-like Protein Lsm8 (Gene symbol: LSM8)
q	1	U6 Snrna-associated Sm-like Protein Lsm2 (Gene symbol: LSM2)
r	1	U6 Snrna-associated Sm-like Protein Lsm3 (Gene symbol: LSM3)
x	1	U6 Snrna-associated Sm-like Protein Lsm6 (Gene symbol: LSM6)
t	1	U6 Snrna-associated Sm-like Protein Lsm5 (Gene symbol: LSM5)
y	1	U6 Snrna-associated Sm-like Protein Lsm7 (Gene symbol: LSM7)
s	1	U6 Snrna-associated Sm-like Protein Lsm4 (Gene symbol: LSM4)
O	1	66 KDA U4/u6.u5 Small Nuclear Ribonucleoprotein Component (Gene symbol: SNU66)
d S l	3	Small Nuclear Ribonucleoprotein SM D3 (Gene symbol: SMD3)
a P h	3	Small Nuclear Ribonucleoprotein-associated Protein B (Gene symbol: SMB1)
b Q m	3	Small Nuclear Ribonucleoprotein SM D1 (Gene symbol: SMD1)
c R n	3	Small Nuclear Ribonucleoprotein SM D2 (Gene symbol: SMD2)
e T i	3	Small Nuclear Ribonucleoprotein E (Gene symbol: SME1)
f U j	3	Small Nuclear Ribonucleoprotein F (Gene symbol: SMX3)
g V k	3	Small Nuclear Ribonucleoprotein G (Gene symbol: SMX2)
D	1	Pre-mrna-splicing Helicase Brr2 (Gene symbol: BRR2)
1	1	U2 Snrnp Component Hsh155 (Gene symbol: HSH155)
2	1	Cold Sensitive U2 Snrna Suppressor 1 (Gene symbol: CUS1)
3	1	Pre-mrna-splicing Factor Rse1 (Gene symbol: RSE1)
4	1	Protein Hsh49 (Gene symbol: HSH49)
5	1	Pre-mrna-splicing Factor Rds3 (Gene symbol: RDS3)
6	1	Rds3 Complex Subunit 10 (Gene symbol: YSF3)
X	1	U2 Snrnp Component Ist3 (Gene symbol: IST3)
Y	1	Pre-mrna-splicing Factor Cwc26 (Gene symbol: BUD13)
Z	1	Pre-mrna Leakage Protein 1 (Gene symbol: PML1)
o	1	U2 Small Nuclear Ribonucleoprotein A' (Gene symbol: LEA1)
p	1	U2 Small Nuclear Ribonucleoprotein B'' (Gene symbol: MSL1)
u	1	Pre-mrna-splicing Factor Prp9 (Gene symbol: PRP9)
w	1	Pre-mrna-splicing Factor Prp21 (Gene symbol: PRP21)
v	1	Pre-mrna-splicing Factor Prp11 (Gene symbol: PRP11)
W	1	23 KDA U4/u6.u5 Small Nuclear Ribonucleoprotein Component (Gene symbol: SNU23)
0	1	Pre-mrna-splicing Factor 38 (Gene symbol: PRP38)
9	1	Pre-mrna-splicing Factor Spp381 (Gene symbol: SPP381)
Nucleotides(5 molecules)
F	1	U6 Snrna
B	1	U5 Snrna
I	1	U4 Snrna
G	1	Pre-mrna
H	1	U2 Snrna
Chemicals and Non-standard biopolymers (2 molecules)
1	1	GUANOSINE-5'-TRIPHOSPHATE
2	1	MAGNESIUM ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB

Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303