6A4I: Crystal Structure of human TDO inhibitor complex

PDB ID: 6A4IDownload
MMDB ID: 164482
PDB Deposition Date: 2018/6/20
Updated in MMDB: 2018/08
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 6A4I: tetrameric; determined by author and by software (PISA)
Molecular Components in 6A4I
Label Count Molecule
Proteins (4 molecules)
4
Tryptophan 2,3-dioxygenase
(Gene symbol: TDO2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
4
1-(6-chloro-1H-indazol-4-yl)cyclohexan-1-ol1-(6-chloro-1H-indazol-4-yl)cyclohexan-1-ol
3
3
TRYPTOPHANTRYPTOPHAN
4
1
CITRIC ACIDCITRIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303