6B1U: Structure of full-length human AMPK (a2b1g1) in complex with a small molecule activator SC4

PDB ID: 6B1UDownload
MMDB ID: 161304
PDB Deposition Date: 2017/9/19
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.77  Å
Source Organism:
Similar Structures:
Biological Unit for 6B1U: trimeric; determined by author and by software (PISA)
Molecular Components in 6B1U
Label Count Molecule
Proteins (3 molecules)
1
5'-amp-activated Protein Kinase Catalytic Subunit Alpha-2
(Gene symbol: PRKAA2)
Molecule annotation
1
5'-amp-activated Protein Kinase Subunit Beta-1
(Gene symbol: PRKAB1)
Molecule annotation
1
5'-amp-activated Protein Kinase Subunit Gamma-1
(Gene symbol: PRKAG1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
STAUROSPORINESTAUROSPORINE
2
1
5-{[6-chloro-5-(2'-hydroxy[1,1'-biphenyl]-4-yl)-1H-imidazo[4,5-b]pyridin-2-yl]oxy}-2-methylbenzoic acid5-{[6-chloro-5-(2'-hydroxy[1,1'-biphenyl]-4-yl)-1H-imidazo[4,5-b]pyridin-2-yl]oxy}-2-methylbenzoic acid
3
2
ADENOSINE MONOPHOSPHATEADENOSINE MONOPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303