6CHI: Human Cytochrome P450 17A1 in complex with inhibitor: abiraterone C6 amide

PDB ID: 6CHIDownload
MMDB ID: 162976
PDB Deposition Date: 2018/2/22
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.698  Å
Source Organism:
Similar Structures:
Biological Unit for 6CHI: monomeric; determined by author and by software (PISA)
Molecular Components in 6CHI
Label Count Molecule
Protein (1 molecule)
1
Steroid 17-alpha-hydroxylase/17,20 Lyase
(Gene symbol: CYP17A1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
1
3-hydroxy-17-(3-pyridyl)-androst-5,16-dien-6-amide3-hydroxy-17-(3-pyridyl)-androst-5,16-dien-6-amide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303