6CZ3: Structure of the PTK6 kinase domain bound to a type I inhibitor (3-fluoro-4-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone

PDB ID: 6CZ3Download
MMDB ID: 163621
PDB Deposition Date: 2018/4/7
Updated in MMDB: 2018/06
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 6CZ3: monomeric; determined by author and by software (PISA)
Molecular Components in 6CZ3
Label Count Molecule
Protein (1 molecule)
1
Protein-tyrosine Kinase 6
(Gene symbol: PTK6)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
(3-fluoro-4-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone(3-fluoro-4-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone
2
7
ACETATE IONACETATE ION
3
2
POTASSIUM IONPOTASSIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303