6DXK: Glucocorticoid Receptor in complex with Compound 11

PDB ID: 6DXKDownload
MMDB ID: 167209
PDB Deposition Date: 2018/6/29
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.05  Å
Source Organism:
Similar Structures:
Biological Unit for 6DXK: dimeric; determined by author and by software (PISA)
Molecular Components in 6DXK
Label Count Molecule
Proteins (2 molecules)
2
Glucocorticoid Receptor
(Gene symbol: NR3C1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-(3,3-dimethylbut-1-yn-1-yl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)(8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-(3,3-dimethylbut-1-yn-1-yl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303