6DXX: Human N-acylethanolamine-hydrolyzing acid amidase (NAAA) in complex with non-covalent benzothiazole-piperazine inhibitor ARN19702, in presence of Triton X-100

PDB ID: 6DXXDownload
MMDB ID: 167000
PDB Deposition Date: 2018/7/1
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6DXX: dimeric; determined by author and by software (PISA)
Molecular Components in 6DXX
Label Count Molecule
Proteins (2 molecules)
1
N-acylethanolamine-hydrolyzing Acid Amidase Subunit Alpha
(Gene symbol: NAAA)
Molecule annotation
1
N-acylethanolamine-hydrolyzing Acid Amidase Subunit Beta
(Gene symbol: NAAA)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
CHLORIDE IONCHLORIDE ION
3
1
2-{2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY}ETHANOL2-{2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY}ETHANOL
4
1
[2-(ethylsulfonyl)phenyl][(2S)-4-(6-fluoro-1,3-benzothiazol-2-yl)-2-methylpiperazin-1-yl]methanone[2-(ethylsulfonyl)phenyl][(2S)-4-(6-fluoro-1,3-benzothiazol-2-yl)-2-methylpiperazin-1-yl]methanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303