6EHH: Crystal structure of mouse MTH1 mutant L116M with inhibitor TH588

PDB ID: 6EHHDownload
MMDB ID: 158136
PDB Deposition Date: 2017/9/13
Updated in MMDB: 2018/02
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 6EHH: monomeric; determined by author and by software (PISA)
Molecular Components in 6EHH
Label Count Molecule
Protein (1 molecule)
1
7,8-dihydro-8-oxoguanine Triphosphatase
(Gene symbol: Nudt1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
N~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamineN~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine
2
7
NITRATE IONNITRATE ION
3
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303