6FER: Crystal Structure of human DDR2 kinase in complex with 2-[4,5-difluoro-2-oxo-1'-(1H-pyrazolo[3,4-b]pyridine-5-carbonyl)spiro[indole-3,4'-piperidine]-1-yl]-N-(2,2,2-trifluoroethyl)acetamide

PDB ID: 6FERDownload
MMDB ID: 169118
PDB Deposition Date: 2018/1/3
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 2.87  Å
Source Organism:
Similar Structures:
Biological Unit for 6FER: monomeric; determined by author
Molecular Components in 6FER
Label Count Molecule
Protein (1 molecule)
1
Discoidin Domain-containing Receptor 2
(Gene symbol: DDR2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[4,5-bis(fluoranyl)-2-oxidanylidene-1'-(1~{H}-pyrazolo[3,4-b]pyridin-5-ylcarbonyl)spiro[indole-3,4'-piperidine]-1-yl]-~{N}-[2,2,2-tris(fluoranyl)ethyl]ethanamide2-[4,5-bis(fluoranyl)-2-oxidanylidene-1'-(1~{H}-pyrazolo[3,4-b]pyridin-5-ylcarbonyl)spiro[indole-3,4'-piperidine]-1-yl]-~{N}-[2,2,2-tris(fluoranyl)ethyl]ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303