6IMZ: Crystal structure of MTH1 in complex with 18-Crown-6

PDB ID: 6IMZDownload
MMDB ID: 180818
PDB Deposition Date: 2018/10/24
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6IMZ: monomeric; determined by author and by software (PISA)
Molecular Components in 6IMZ
Label Count Molecule
Protein (1 molecule)
1
7,8-dihydro-8-oxoguanine Triphosphatase
(Gene symbol: NUDT1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
3
ZINC IONZINC ION
2
1
SULFATE IONSULFATE ION
3
2
1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE
4
1
3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303