6JVS: Crystal structure of human MTH1 in complex with compound MI1029

PDB ID: 6JVSDownload
MMDB ID: 194330
PDB Deposition Date: 2019/4/17
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6JVS: monomeric; determined by author
Molecular Components in 6JVS
Label Count Molecule
Protein (1 molecule)
1
7,8-dihydro-8-oxoguanine Triphosphatase
(Gene symbol: NUDT1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N4-cyclopropyl-6-[4-(oxetan-3-yl)piperazin-1-yl]pyrimidine-2,4-diamineN4-cyclopropyl-6-[4-(oxetan-3-yl)piperazin-1-yl]pyrimidine-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303