6KTN: Human PPARgamma ligand-binding domain R288A mutant in complex with imatinib

PDB ID: 6KTNDownload
MMDB ID: 183811
PDB Deposition Date: 2019/8/28
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.752  Å
Source Organism:
Similar Structures:
Biological Unit for 6KTN: dimeric; determined by author and by software (PISA)
Molecular Components in 6KTN
Label Count Molecule
Proteins (2 molecules)
1
Peroxisome Proliferator-activated Receptor Gamma
(Gene symbol: PPARG)
Molecule annotation
1
16-mer Peptide From Nuclear Receptor Coactivator 1
(Gene symbol: NCOA1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303