6KZD: Crystal structure of TRKc in complex with 3-((6-(4-aminophenyl)imidazo[1,2-a]pyrazin-3-yl)ethynyl)- N-(3-isopropyl-5-((4-methylpiperazin-1-yl)methyl)phenyl)-2- methylbenzamide

PDB ID: 6KZDDownload
MMDB ID: 180283
PDB Deposition Date: 2019/9/23
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 1.708  Å
Source Organism:
Similar Structures:
Biological Unit for 6KZD: monomeric; determined by author and by software (PISA)
Molecular Components in 6KZD
Label Count Molecule
Protein (1 molecule)
1
Nt-3 Growth Factor Receptor
(Gene symbol: NTRK3)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
3-[2-[6-(4-aminophenyl)imidazo[1,2-a]pyrazin-3-yl]ethynyl]-2-methyl-~{N}-[3-(4-methylpiperazin-1-yl)-5-propan-2-yl-phenyl]benzamide3-[2-[6-(4-aminophenyl)imidazo[1,2-a]pyrazin-3-yl]ethynyl]-2-methyl-~{N}-[3-(4-methylpiperazin-1-yl)-5-propan-2-yl-phenyl]benzamide
2
1
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303