6LRL: Human cGAS catalytic domain bound with compound s2

PDB ID: 6LRLDownload
MMDB ID: 189181
PDB Deposition Date: 2020/1/16
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.655  Å
Source Organism:
Similar Structures:
Biological Unit for 6LRL: dimeric; determined by author
Molecular Components in 6LRL
Label Count Molecule
Proteins (2 molecules)
2
Cyclic Gmp-amp Synthase
(Gene symbol: CGAS)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
ZINC IONZINC ION
2
1
3-[[5-(1,2,4-triazol-4-yl)-4H-1,2,4-triazol-3-yl]carbonylamino]benzoic acid3-[[5-(1,2,4-triazol-4-yl)-4H-1,2,4-triazol-3-yl]carbonylamino]benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303