6M49: cryo-EM structure of Scap/Insig complex in the present of 25-hydroxyl cholesterol

PDB ID: 6M49Download
MMDB ID: 197640
PDB Deposition Date: 2020/3/6
Updated in MMDB: 2024/04
Experimental Method:
electron microscopy
Resolution: 3.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6M49: dimeric; determined by author
Molecular Components in 6M49
Label Count Molecule
Proteins (2 molecules)
1
Insulin-induced Gene 2 Protein
(Gene symbol: INSIG2)
Molecule annotation
1
Sterol Regulatory Element-binding Protein Cleavage-activating Protein,sterol Regulatory Element-binding Protein Cleavage-activating Protein
(Gene symbol: SCAP)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
25-HYDROXYCHOLESTEROL25-HYDROXYCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303