6MFR: Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3)

PDB ID: 6MFRDownload
MMDB ID: 178208
PDB Deposition Date: 2018/9/12
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.6  Å
Source Organism:
unidentified▼
Similar Structures:
Biological Unit for 6MFR: trimeric; determined by author and by software (PISA)
Molecular Components in 6MFR
Label Count Molecule
Protein (1 molecule)
1
Protein Argonaute-2
Molecule annotation
Nucleotides(2 molecules)
1
RNA (5'-r(p*up*gp*gp*ap*gp*up*gp*up*gp*ap*cp*ap*ap*up*gp*gp*up*gp*up*u)-3')
Molecule annotation
1
RNA (5'-r(p*ap*ap*ap*cp*ap*cp*cp*ap*up*up*up*up*cp*ap*cp*ap*cp*up*cp*cp*ap*ap*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
PHENOLPHENOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303