6MX3: Crystal structure of human STING (G230A, H232R, R293Q) in complex with Compound 1

PDB ID: 6MX3Download
MMDB ID: 169916
PDB Deposition Date: 2018/10/30
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 1.362  Å
Source Organism:
Similar Structures:
Biological Unit for 6MX3: dimeric; determined by author and by software (PISA)
Molecular Components in 6MX3
Label Count Molecule
Proteins (2 molecules)
2
Stimulator of Interferon Genes Protein
(Gene symbol: STING1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
(3S,4S)-2-(4-tert-butylphenyl)-3-(4-methoxyphenyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid(3S,4S)-2-(4-tert-butylphenyl)-3-(4-methoxyphenyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid
2
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303