6PB1: Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35

PDB ID: 6PB1Download
MMDB ID: 184096
PDB Deposition Date: 2019/6/12
Updated in MMDB: 2020/02
Experimental Method:
electron microscopy
Resolution: 2.8  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6PB1: hexameric; determined by author
Molecular Components in 6PB1
Label Count Molecule
Proteins (6 molecules)
1
Corticotropin-releasing Factor Receptor 2
Molecule annotation
1
Urocortin
Molecule annotation
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short,guanine Nucleotide-binding Protein G(i) Subunit Alpha-1,guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Nanobody 35
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
4
CHOLESTEROLCHOLESTEROL
2
5
PALMITIC ACIDPALMITIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303