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6POZ:
Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-isopropoxyphenyl)-4-methylquinolin-2-amine
PDB ID:
6POZ
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MMDB ID:
187013
PDB Deposition Date:
2019/7/5
Updated in MMDB:
2023/10
Experimental Method:
x-ray diffraction
Resolution:
2.2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6POZ: dimeric; determined by author and by software (PISA)
Molecular Components in 6POZ
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Nitric Oxide Synthase, Endothelial
(Gene symbol:
NOS3
)
Chemicals and Non-standard biopolymers (17 molecules)
1
2
PROTOPORPHYRIN IX CONTAINING FE
2
1
5,6,7,8-TETRAHYDROBIOPTERIN
3
3
7-{3-(aminomethyl)-4-[(propan-2-yl)oxy]phenyl}-4-methylquinolin-2-amine
4
6
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
5
1
ZINC ION
6
1
GLYCEROL
7
2
CHLORIDE ION
8
1
GADOLINIUM ATOM
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303