6PYZ: Crystal Structure of human Tryptophan 2,3-dioxygenase in complex with PF-06840003 in Active Site

PDB ID: 6PYZDownload
MMDB ID: 182747
PDB Deposition Date: 2019/7/31
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.02  Å
Source Organism:
Similar Structures:
Biological Unit for 6PYZ: tetrameric; determined by author and by software (PISA)
Molecular Components in 6PYZ
Label Count Molecule
Proteins (4 molecules)
4
Tryptophan 2,3-dioxygenase
(Gene symbol: TDO2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
4
(3S)-3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione(3S)-3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione
3
4
alpha-methyl-L-tryptophanalpha-methyl-L-tryptophan
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303