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6R7H:
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
PDB ID:
6R7H
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MMDB ID:
178977
PDB Deposition Date:
2019/3/28
Updated in MMDB:
2019/09
Experimental Method:
electron microscopy
Resolution:
8.8 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Molecular Components in 6R7H
Label
Count
Molecule
Proteins (12 molecules)
A
1
Cop9 Signalosome Complex Subunit 1
(Gene symbol:
GPS1
)
Q
1
Elongin-c
(Gene symbol:
ELOC
)
O
1
Cullin-2
(Gene symbol:
CUL2
)
R
1
E3 Ubiquitin-protein Ligase Rbx1
B
1
Cop9 Signalosome Complex Subunit 2
(Gene symbol:
COPS2
)
C
1
Cop9 Signalosome Complex Subunit 3
(Gene symbol:
COPS3
)
D
1
Cop9 Signalosome Complex Subunit 4
(Gene symbol:
COPS4
)
E
1
Cop9 Signalosome Complex Subunit 5
(Gene symbol:
COPS5
)
F
1
Cop9 Signalosome Complex Subunit 6
(Gene symbol:
COPS6
)
G
1
Cop9 Signalosome Complex Subunit 7B
(Gene symbol:
COPS7B
)
H
1
Cop9 Signalosome Complex Subunit 8
(Gene symbol:
COPS8
)
P
1
Elongin-b
(Gene symbol:
ELOB
)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303