6TQ4: Crystal structure of the Orexin-1 receptor in complex with Compound 16

PDB ID: 6TQ4Download
MMDB ID: 182800
PDB Deposition Date: 2019/12/16
Updated in MMDB: 2020/03
Experimental Method:
x-ray diffraction
Resolution: 2.299  Å
Source Organism:
Similar Structures:
Biological Unit for 6TQ4: monomeric; determined by author
Molecular Components in 6TQ4
Label Count Molecule
Protein (1 molecule)
1
Orexin Receptor Type 1
(Gene symbol: HCRTR1)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
1
2-[1-(phenylsulfonyl)-1,8-diazaspiro[4.5]decan-8-yl]-1,3-benzoxazole2-[1-(phenylsulfonyl)-1,8-diazaspiro[4.5]decan-8-yl]-1,3-benzoxazole
2
2
SULFATE IONSULFATE ION
3
2
(1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate(1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate
4
10
octyl 1-thio-beta-D-glucopyranosideoctyl 1-thio-beta-D-glucopyranoside
5
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303