6TQ6: Crystal structure of the Orexin-1 receptor in complex with Compound 14

PDB ID: 6TQ6Download
MMDB ID: 182801
PDB Deposition Date: 2019/12/16
Updated in MMDB: 2020/03
Experimental Method:
x-ray diffraction
Resolution: 2.546  Å
Source Organism:
Similar Structures:
Biological Unit for 6TQ6: monomeric; determined by author
Molecular Components in 6TQ6
Label Count Molecule
Protein (1 molecule)
1
Orexin Receptor Type 1
(Gene symbol: HCRTR1)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
2-(5-methylsulfonylpyridin-3-yl)-1,1-bis(oxidanylidene)-4-[[2,4,6-tris(fluoranyl)phenyl]methyl]pyrido[2,3-e][1,2,4]thiadiazin-3-one2-(5-methylsulfonylpyridin-3-yl)-1,1-bis(oxidanylidene)-4-[[2,4,6-tris(fluoranyl)phenyl]methyl]pyrido[2,3-e][1,2,4]thiadiazin-3-one
2
2
SULFATE IONSULFATE ION
3
2
(1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate(1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate
4
5
octyl 1-thio-beta-D-glucopyranosideoctyl 1-thio-beta-D-glucopyranoside
5
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303