6WGL: Dupilumab fab with Crystal Kappa design complexed with human IL-4 receptor

PDB ID: 6WGLDownload
MMDB ID: 192383
PDB Deposition Date: 2020/4/5
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.82  Å
Source Organism:
Similar Structures:
Biological Unit for 6WGL: pentameric; determined by author and by software (PISA)
Molecular Components in 6WGL
Label Count Molecule
Proteins (5 molecules)
2
Dupilumab FAB Heavy Chain
Molecule annotation
2
Dupilumab FAB Light Chain
Molecule annotation
1
Interleukin-4 Receptor Subunit Alpha
(Gene symbol: IL4R)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
5
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303