6XOG: Structure of SUMO1-ML786519 adduct bound to SAE

PDB ID: 6XOGDownload
MMDB ID: 199548
PDB Deposition Date: 2020/7/7
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.98  Å
Source Organism:
Similar Structures:
Biological Unit for 6XOG: trimeric; determined by author and by software (PISA)
Molecular Components in 6XOG
Label Count Molecule
Proteins (3 molecules)
1
Sumo-activating Enzyme Subunit 1
(Gene symbol: SAE1)
Molecule annotation
1
Sumo-activating Enzyme Subunit 2
(Gene symbol: UBA2)
Molecule annotation
1
Small Ubiquitin-related Modifier 1
(Gene symbol: SUMO1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
SULFATE IONSULFATE ION
2
1
ZINC IONZINC ION
3
1
{(1R,2R,3S,4R)-4-[(5-{4-[(1S)-1-(6-bromopyridin-2-yl)-1-hydroxyethyl]thiophene-2-carbonyl}pyrimidin-4-yl)amino]-2,3-dihydroxycyclopentyl}methyl sulfamate{(1R,2R,3S,4R)-4-[(5-{4-[(1S)-1-(6-bromopyridin-2-yl)-1-hydroxyethyl]thiophene-2-carbonyl}pyrimidin-4-yl)amino]-2,3-dihydroxycyclopentyl}methyl sulfamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303