6XVF: Crystal structure of bovine cytochrome bc1 in complex with tetrahydro-quinolone inhibitor JAG021

PDB ID: 6XVFDownload
MMDB ID: 190469
PDB Deposition Date: 2020/1/21
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6XVF: eicosameric; determined by author and by software (PISA)
Molecular Components in 6XVF
Label Count Molecule
Proteins (20 molecules)
2
Cytochrome B-c1 Complex Subunit 1, Mitochondrial
(Gene symbol: UQCRC1)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit 2, Mitochondrial
(Gene symbol: UQCRC2)
Molecule annotation
2
Cytochrome B
(Gene symbol: CYTB)
Molecule annotation
2
Cytochrome C1, Heme Protein, Mitochondrial
(Gene symbol: CYC1)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit Rieske, Mitochondrial
(Gene symbol: UQCRFS1)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit 7
(Gene symbol: UQCRB)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit 8
(Gene symbol: UQCRQ)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit 6, Mitochondrial
(Gene symbol: UQCRH)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit Rieske, Mitochondrial
(Gene symbol: UQCRFS1)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit 9
(Gene symbol: UQCR10)
Molecule annotation
Chemicals and Non-standard biopolymers (52 molecules)
1
6
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
2
2
1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
3
18
PHOSPHATE IONPHOSPHATE ION
4
8
CARDIOLIPINCARDIOLIPIN
5
4
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
6
2
DODECYL-BETA-D-MALTOSIDEDODECYL-BETA-D-MALTOSIDE
7
4
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
8
2
2-methyl-3-[4-[4-(trifluoromethyloxy)phenoxy]phenyl]-5,6,7,8-tetrahydro-3~{H}-quinolin-4-one2-methyl-3-[4-[4-(trifluoromethyloxy)phenoxy]phenyl]-5,6,7,8-tetrahydro-3~{H}-quinolin-4-one
9
2
HEME CHEME C
10
2
FE2/S2 (INORGANIC) CLUSTERFE2/S2 (INORGANIC) CLUSTER
11
2
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303