6Y5E: Structure of human cGAS (K394E) bound to the nucleosome (focused refinement of cGAS-NCP subcomplex)

PDB ID: 6Y5EDownload
MMDB ID: 193178
PDB Deposition Date: 2020/2/25
Updated in MMDB: 2024/09
Experimental Method:
electron microscopy
Resolution: 3.15  Å
Source Organism:
Similar Structures:
Biological Unit for 6Y5E: undecameric; determined by author
Molecular Components in 6Y5E
Label Count Molecule
Proteins (9 molecules)
2
Histone H3.2
(Gene symbol: H3C14)
Molecule annotation
1
Histone H4
(Gene symbol: H4C9)
Molecule annotation
1
Histone H2A Type 2-C
(Gene symbol: H2AC20)
Molecule annotation
1
Histone H2B Type 1-K
(Gene symbol: H2BC12)
Molecule annotation
1
Histone H4
(Gene symbol: H4C9)
Molecule annotation
1
Histone H2A Type 2-C
(Gene symbol: H2AC20)
Molecule annotation
1
Histone H2B Type 1-K
(Gene symbol: H2BC12)
Molecule annotation
1
Cyclic Gmp-amp Synthase
(Gene symbol: CGAS)
Molecule annotation
Nucleotides(2 molecules)
1
DNA (153-mer)
Molecule annotation
1
DNA (153-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
8
PENTANEDIALPENTANEDIAL
2
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303